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development of IAA was get more info considered possible as a result of oxidase deamination of NMT (Barker et al., 1980), but was later recognized to become also in part by direct deamination by MAO (Barker et al., 1982). Pretreatment While using the MAO-I iproniazid in rat full brain homogenates inhibited IAA development by 83%, NMT and DMT-NO for